[HTML][HTML] Molecular alterations in gastric preneoplastic lesions and early gastric cancer
S Battista, MR Ambrosio, F Limarzi, G Gallo… - … journal of molecular …, 2021 - mdpi.com
… mutations in the tumor suppressor gene CDH1, although … in preneoplastic and neoplastic
lesions of the stomach, with … parameters, microsatellite status, and frequency of TP53 mutations …
lesions of the stomach, with … parameters, microsatellite status, and frequency of TP53 mutations …
[HTML][HTML] Targeted genetic and epigenetic profiling of esophageal adenocarcinomas and non-dysplastic Barrett's esophagus
R Pinto, T Hauge, M Jeanmougin, HD Pharo… - Clinical …, 2022 - Springer
… of selected genetic (TP53 mutations and microsatellite … the lower esophagus is replaced by
specialized columnar intestinal … As for other solid cancer types, the TP53 tumor suppressor is …
specialized columnar intestinal … As for other solid cancer types, the TP53 tumor suppressor is …
Molecular evolution of metaplasia to adenocarcinoma in the esophagus
WM Grady, M Yu - Digestive diseases and sciences, 2018 - Springer
… that numerous tumor suppressor genes exhibit aberrant … from normal esophageal lining, to
specialized intestinal metaplasia, … as the p53 positivity rate in Barrett’s esophagus dysplasia is …
specialized intestinal metaplasia, … as the p53 positivity rate in Barrett’s esophagus dysplasia is …
[HTML][HTML] The mismatch repair system (MMR) in head and neck carcinogenesis and its role in modulating the response to immunotherapy: a critical review
M Cilona, LG Locatello, L Novelli, O Gallo - Cancers, 2020 - mdpi.com
… of specific genetic sequences, known as microsatellites, and … such as colon, stomach, prostate,
esophagus, endometrium, … of oncogenes/tumor suppressor genes such as p16 and p53. …
esophagus, endometrium, … of oncogenes/tumor suppressor genes such as p16 and p53. …
[HTML][HTML] Molecular landscapes of gastric pre-neoplastic and pre-invasive lesions
G Businello, V Angerilli, P Parente, S Realdon… - … Journal of Molecular …, 2021 - mdpi.com
… microsatellite unstable (MSI) tumors (23%), (ii) microsatellite … reported to act as a tumor
suppressor and to be dysregulated … are benign neoplasms of the upper third of the stomach …
suppressor and to be dysregulated … are benign neoplasms of the upper third of the stomach …
[PDF][PDF] Gastric intestinal metaplasia: an intermediate precancerous lesion in the cascade of gastric carcinogenesis
TH Malik, MY Sayahan, HA Al Ahmed, X Hong - J Coll Physicians Surg Pak, 2017 - jcpsp.pk
… to) p53, homeobox gene (Cdx2), microsatellite instability and … Mutation in p53 (tumor
suppressor gene) is usually observed … , dysplastic and even neoplastic lesions in the stomach. …
suppressor gene) is usually observed … , dysplastic and even neoplastic lesions in the stomach. …
Intestinal‐type sinonasal adenocarcinomas: The road to molecular diagnosis and personalized treatment
A Hoeben, L van de Winkel, F Hoebers, K Kross… - Head & …, 2016 - Wiley Online Library
… from reflux esophagitis toward esophageal adenocarcinoma … These genes are known tumor
suppressor genes that not … allows mutations to accumulate in microsatellite sequences. It is …
suppressor genes that not … allows mutations to accumulate in microsatellite sequences. It is …
Genomics of esophageal cancer and biomarkers for early detection
… of a number of tumor suppressor genes, cell cycle regulators, … frame p14 ARF lesions (LOH
at microsatellite D9S925, … pathway is responsible for promoting the intestinal architecture [47]. …
at microsatellite D9S925, … pathway is responsible for promoting the intestinal architecture [47]. …
[HTML][HTML] Gastric cancer in the era of precision medicine
X Liu, SJ Meltzer - … and molecular gastroenterology and hepatology, 2017 - Elsevier
… to the proximal stomach, without evidence of colorectal or … by inactivating tumor-suppressor
genes or disrupting other … the frequency of mutations within microsatellite markers, GC can be …
genes or disrupting other … the frequency of mutations within microsatellite markers, GC can be …
[HTML][HTML] Early onset esophageal adenocarcinoma: a distinct molecular entity?
AMJ van Nistelrooij, R van Marion, K Biermann… - …, 2016 - ncbi.nlm.nih.gov
… to the molecular profiles: the tumor suppressor gene TP53 was … established for metastatic
colorectal cancer [19]. The current … the presence of microsatellite instability analyses were …
colorectal cancer [19]. The current … the presence of microsatellite instability analyses were …